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KMID : 0382420010270020037
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Korean Journal of Environmental Health Society
2001 Volume.27 No. 2 p.37 ~ p.42
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Determination of the Bioconcentration Factor in Some Pesticides by Flow-through Fish Test
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Min Kyung-Jin
Cha Chun-Geun
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Abstract
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The present study was performed to investigate the bioconcentration of methidathion and phosalone. The BCFs (bioconcentration factors), depuration rate constants and LC_50 for two pesticides in zebrafish (Brachydanio rerio) were measured by the flow-through system (OECD guideline 305). The results obtained are summarized as follows : The 24-hr LC_50, 48-hr LC_50, 72-hr LC_50 and 96-hr LC_50 were 28.34, 35.98, 24.43, 22.03 for methidathion. The average BCF values of methidathion were 11.25(n=4) and 8.72(n=4) at one-thousandth and one-hundredth concentration of 96-hr LC_50(0.022 mg/ℓ and 0.22 mg/ℓ) after 12~72 hrs. The 24-hr LC_50, 48-hr LC_50, 72-hr LC_50 and 96-hr LC_50 were 3.76, 2.43, 1.86 and 1.05 mg/ℓ for phosalone. The average BCF value of phosalone was 48.88(n=4) at one-hundredth concentration of 96-hr LC_50(0.01 mg/ℓ) after 12~72hrs. However, phosalone was not detected throughout the experimental period at the low concentration(0.001 ㎍/㎖). The LC_50 value in zebrafish showed that acute toxicity of phosalone was higher than that of methidathion. The BCF values of phosalone were 5 times higher than those of methidathion, and depuration rate of phosalone was faster than that of methidathion.
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